Physician Profile

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George A. Stouffer, III, MD

Distinguished Professor

Department of Medicine
    Division of Cardiology

Cardiology (Adult), Heart & Vascular

Interventional cardiology, vascular biology. Smooth muscle cell growth regulation; particularly integrin/cytoskeletal interactions; regulation of thrombin & thrombus formulation during interventions.
Clinical Appointment Phone:  866-862-4327 - UNC Open Access Referral Center
Fax:  919-966-4366
Assistant Name:  Dianne Hunter
Assistant Email:
Assistant Phone:  919-966-5956

George Andrew Stouffer, III, MD

Interventional Cardiology - Board Certified
Cardiovascular Diseases - Board Certified

Education and Training
Fellowship: University of Virginia Health Sciences Center, Charlottesville, VA, 1994 - 1995
Area: Interventional Cardiology
  University of Virginia Health Sciences Center, Charlottesville, VA, 1992 - 1994
Area: Cardiology
  University of Virginia Health Sciences Center, Charlottesville, VA, 1990 - 1992
Area: Cardiovascular Research
Internship and Residency: University of Virginia Health Sciences Center, Charlottesville, VA, 1987 - 1990
Area: Internal Medicine
Medical School: MD, University of Maryland, Baltimore, MD, 1987

Professional Positions
  1. Distinguished Professor of Medicine, Henry A. Foscue Professorship Award

  2. Chief, Cardiology for Clinical Affairs, UNC

  3. Director, Interventional Cardiology, UNC, 2001

  4. Director, C.V. Richardson Cardiac Cath Lab, UNC, 2001

  5. Interim Chief, Division of Cardiology, UNC, 2014

  1. Alpha Omega Alpha

  2. Phi Beta Kappa

  3. Tau Beta Pi National Engineering Honor Society

  4. Omicron Delta kappa National Leadership Honor Society

  5. Fellow, American College of Cardiology

  6. Fellow, American College of Physicians

  7. Fellow, American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology

  8. Fellow, Society for Cardiovascular Angiography and Interventions

  9. Councilor of the NC Chapter of the American College of Cardiology

  10. Executive Council member of Credentials Committee of Society of Cardiovascular Angiography and Interventions

  11. Executive Council member of Interventional Training Standards & Program Directors

  12. Editorial Board, JACC – Cardiovascular Interventions

  13. Committee of Society of Cardiovascular Angiography and Interventions

  1. Percutaneous coronary intervention or coronary artery bypass grafting: Intervention in the elderly with Acute Coronary Syndrome: Part I - Differential diffusing of invasive treatment
    Authors: Sheridan BC, Stearns SC, Massing MW, Stougger GA, D'Arcy LP, Winzelberg GS, Carey TS
    Clinical Geriatrics; October; 39-45, 2008

  2. Percutaneous coronary intervention or coronary artery bypass grafting: Intervention in the elderly with Acute Coronary Syndrome: Part II - Outcomes of invasive treatment
    Authors: Sheridan BC, Stearns SC, Massing MW, Stougger GA, D'Arcy LP, Winzelberg GS, Carey TS
    Clinical Geriatrics; November; 40-47, 2008

  3. Eptifibatide and abciximab inhibit insulin-induced focal adhesion formation and proliferative responses in human aortic smooth muscle cells.
    Authors: Pathak A, Zhao R, Huang J, Stouffer GA
    Cardiovascular Diabetalogy; 7:36, 2008

  4. Scintographic Evidence of Severe Myocardial Hypoperfusion in a Patient with Left Anterior Descending Company Artery Bridging - Case Report and Review of the Literature.
    Authors: Zurick AO, Klein JL and Stouffer GA
    Am J Med Sci; 336:498-502, 2008

  5. A Prospective Randomized Clinical Trial of the Use of Flouroscopy in Obtaining Fermoral Arterial Access.
    Authors: Huggins CE, Gillespie MJ, Tan WA, Laundon RC, Costello FM, Darrah SB, Tate DA, Cohen MG, Stouffer GA
    J Invasive Cardial 21:105-9, 2009

  6. Dominant-negative loss of PPARg funciton enhances smooth muscle cell proliferation, migration and vascular remodeling.
    Authors: Meredith D, Panchatcharam M, Miriyala S, Tsai YS, Maeda N, Stouffer GA, Smyth SS
    Arterioscler Tromb Vasc Bio 29:465-471, 2009

  7. The paradoxical use of cardiac catheterization in patients with non-ST-elevation acute coronary syndromes: lessons from the CRUSADE Quality Improvement Initiative.
    Authors: Cohen MG, Filby SJ, Roe MT, Chen AY, Menon V, Stouffer GA, Gibler WB, Smith SC, Pollack CV, Peterson ED, Ohman EM
    Am. Heart J; 158:263-70, 2009

  8. Optimizing the Use of Thrombolytics in ST-Segment Elevation Myocardial Infarction
    Authors: MA Morse, JW Todd and GA Stouffer
    Drugs, 2009, In Press

  9. Biventricular plus alternans
    Authors: Vidwan P and Stouffer GA
    Cardiology Research and Practice, 2009, In Press

  10. Clopidogrel Pharacogenomics and Risk of Inadequate Platelet Inhibitions: US FDA Recommendation
    Authors: Ellis KJ, Stouffer GA, McLeod HI, Lee CR
    Pharmacogenomics, 2009, IN Press

  11. Unilateral renal artery stenosis causes a chronic vascular inflammatory response in ApoE mice.
    Authors: Stouffer GA, Pathak A, Rojas M.
    Trans Am Clin Climatol Assoc. 2010;121:252-64; 264-6., 2010

  12. Activation of PAR-3 and PAR-4 Accelerates Tissue Factor-induced Thrombin Generation on the Surface of Vascular Smooth Muscle Cells
    Authors: Vidwan P, Pathak A, Sheth S, Huang J, Monroe DM, Stouffer GA.
    Arterioscler Thromb Vasc Bio 2010;30:2587-2596, 2010

  13. Relation of Platelet Count to Bleeding and Vascular Complications in Patients Undergoing Coronary Angiography
    Authors: Vidwan P, Lee S, Rossi JS, Stouffer GA
    Am J Cardiol 2010; 105:1219-1222, 2010

  14. Perivascular Delivery of Blebbistatin Reduces Neointimal Hyperplasia Following Carotid Injury in the Mouse
    Authors: Huang J, Zhang J, Pathak A, Li J, Stouffer GA.
    J Pharmacol Exp Ther. 2011;336:116-26, 2011

  15. Optimal Use of Platelet Glycoprotein IIb/IIIa Receptor Antagonists in Patients Undergoing Percutaneous Coronary Interventions,
    Authors: Starnes HB, Patel A, Stouffer GA.
    Drugs 2011;71:2009-2030, 2011

  16. Relation between Digital Peripheral Arterial Tonometry and Brachial Artery Ultrasound Measures of Vascular Function in Patients with Coronary Artery Disease and in Healthy Volunteers
    Authors: Lee CR, Bass A, Ellis K, Tran B, Steele S, Caughey M, Stouffer GA, Hinderliter AL.
    Am J Cardiol 2012;109:651-657, 2012

  17. Regional Approach to Cardiovascular Emergencies (RACE) Investigators. Expansion of a regional ST-segment-elevation myocardial infarction system to an entire state.
    Authors: Jollis JG, Al-Khalidi HR, Monk L, Roettig ML, Garvey JL, Aluko AO, Wilson BH, Applegate RJ, Mears G, Corbett CC, Granger CB.
    Circulation. 2012;126:189-95., 2012

  18. Evaluation of cytochrome p450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease
    Authors: Theken KN, Schuck RN, Edin ML, Tran B, Ellis K, Bass A, Lih FB, Tomer KB, Poloyac SM, Wu MC, Hinderliter AL, Zeldin DC, Stouffer GA, Lee CR.
    Atherosclerosis 2012;222:530-536, 2012

  19. Relation of Pulse, Systolic and Mean Blood Pressure to Severe Renal Artery Stenosis in Patients Undergoing Concurrent Coronary and Renal Angiography
    Authors: Bazemore TC, Meredith D, Bumgarner JM, Stouffer GA.
    Am J Cardiol 2013;111:1547-1551, 2013

  20. Cytochrome p450-derived eicosanoids and vascular dysfunction in coronary artery disease patients
    Authors: Schuck RN, Theken KN, Edin ML, Caughey M, Bass A, Ellis K, Tran B, Steele S, Simmons BP, Lih FB, Tomer KB, Wu MC, Hinderliter AL, Stouffer GA, Zeldin DC, Lee CR.
    Atherosclerosis 2013;227:442-448, 2013

  21. Acute ST Elevation Myocardial Infarction In Patients Hospitalized for Non-cardiac Conditions
    Authors: Dai X, Bumgarner J, Spangler A, Meredith D, Smith SC, Stouffer GA.
    Journal of the American Heart Association; 2013;2:e000004., 2013

  22. Hemodynamic Findings in Severe Tricuspid Regurgitation
    Authors: Rao S, Tate DA, Stouffer GA.
    Cathet Cardiovasc Intervent 2013;81:162-169, 2013

  23. Catheter-based Renal Denervation in the Treatment of Resistant Hypertension
    Authors: Stouffer GA, DiBona GF, Patel A, Kaul P, Hinderliter AL.
    J Mol Cell Cardiol. 2013;62:18-23, 2013

  24. Is time of renal hypoperfusion an important variable in determining response to renal artery revascularization?
    Authors: Zhou R and Stouffer GA.
    JACC-Cardiovascular Interventions 2014;7:110, 2014

  25. Clopidogrel Dose Adjustment after Outpatient Screening for CYP2C19 Variant Alleles: A Pilot Study
    Authors: Rossi JS, Cammarata M, Dharmavaram J, Weck K, Walko C, Gabriel D, Kuritzky J, Muldrew K, Stouffer GA.
    Pharmacogenomics 2014; in press, 2014

Physician Referral:
You can request a physician referral by calling UNC HealthLink at (919) 966-7890,
8:30 a.m. to 5 p.m., Monday through Friday.