Physician Profile

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Cam Patterson, MD, MBA, FACC, FAHA

Ernest and Hazel Craige Distinguished Professor; Associate Dean, Health Care Entrepreneurship; Physician-in-Chief, UNC Center for Heart and Vascular Care; Division Chief; Associate Chair, Research

Department of Medicine
Department of Medicine
    Division of Cardiology

Cardiology (Adult), Heart & Vascular, Cardiac Genetics

Cardiac genetics, angiogenesis, vascular biology, endothelium, atherosclerosis. Patterson lab: molecular, genetic, & physiologic approaches to investigate the processes of angiogenesis, cardiac failure, and atherosclerosis.
Clinical Appointment Phone:  866-862-4327 - UNC Open Access Referral Center
Fax:  919-843-4164
Assistant Name:  Janice Sanford
Assistant Phone:  919-843-5201
Assistant Email:

Cam Patterson, MD, MBA

Internal Medicine - Board Certified  (1989)
Cardiovascular Diseases - Board Certified  (2001)

Education and Training
Masters: MBA, University of North Carolina, Chapel Hill, NC, 2008
Area: Business
Fellowship: University of Texas, Galveston, TX, 1997 - 1999
Area: Cardiology
  Harvard School of Public Health, Boston, MA, 1994 - 1996
Area: Cardiovascular Biology
Chief Residency: Emory University School of Medicine, Atlanta, GA, 1992 - 1993
Area: Internal Medicine
Internship and Residency: Emory University School of Medicine, Atlanta, GA, 1990 - 1992
Area: Internal Medicine
Medical School: MD, Emory University School of Medicine, Atlanta, GA, 1989

Professional Positions
  1. Chief, Division of Cardiology, UNC, 2005

  2. Ernest and Hazel Craige Distinguished Professor of Cardiovascular Medicine, UNC, 2005

  3. Physician-in-Chief, UNC Center for Heart & Vascular Care, UNC, 2008

  4. Associate Dean, Health Care Entrepreneurship, UNC, 2010

  1. CHIP-mediated stress recovery by hierarchical substrate-dependent autoregulation of Hsp70
    Authors: Qian S-B, McDonough H, Boellman F, Cyr DM, Patterson C.
    Journal of Cell Biology (Nature, 440:551-555), 2006

  2. Folding defects in CFTR are recognized by distinct quality control complexes that contain the ER membrane associated E3 ubiquitin ligase RMA1 and the cytosolic E3 CHIP
    Authors: Younger JM, Ren RJ, Patterson C, Cyr D.
    Cell, 126: 571-582, 2006

  3. Gene expression profiles identify a role for cyclooxygenase 2-dependent prostanoid generation in BMP6-induced angiogenic responses
    Authors: Ren R, Charles PC, Zhang C, Wu Y, Wang H, Koller BH, Patterson C.
    Blood, 109: 2847-2853, 2007

  4. Ankyrin Repeat and SOCS Box Protein 4 (ASB4) is a Hydroxylation Substrate of Factor Inhibiting HIF1a (FIH) and Promotes Vascular Differentation via an Oxygen-Dependent Mechanism
    Authors: Ferguson J, Wu Y, Smith K, Charles P, Powers K, Wang H, Patterson C.
    Molecular and Cellular Biology, 27: 6407-7419, 2007

  5. Astrogin-1/Muscle atrophy F-box inhibits Akt-dependent cardiac hypertrophy via ubiquitin-dependent co-activation of Forkhead proteins.
    Authors: Li H-H, Willis MS, Lockyear P, Miller N, McDonough H, Glass D, Patterson C.
    Journal of Clinical Investigation 117: 3211-3223, 2007

  6. Wnt2 coordinates the commitment of mesoderm to hemtopoietic, endothelial, and cardiac lineages in embryoid bodies
    Authors: Wang H, Gilner JB, Bautch VL, Wang D-Z, Wainwright BJ, Kirby SL, Patterson C.
    Journal of Biological Chemistry, 282: 782-291, 2007

  7. CHIP deficiency decreases longevity with accelerated aging phenotypes accom-panied by altered protein quality control
    Authors: Min J-N, Whaley RA, Sharpless NE, Lockyer P, Portbury AL, Patterson C.
    Molecular and Cellular Biology, 28: 4018-4025, 2008

Physician Referral:
You can request a physician referral by calling UNC HealthLink at (919) 966-7890,
8:30 a.m. to 5 p.m., Monday through Friday.